Last edited by Nelabar
Friday, July 24, 2020 | History

4 edition of Animal Models of Neuropsychiatric Diseases found in the catalog.

Animal Models of Neuropsychiatric Diseases

by Michael Koch

  • 345 Want to read
  • 27 Currently reading

Published by Imperial College Press .
Written in English

    Subjects:
  • Neurology & clinical neurophysiology,
  • Neurosciences,
  • Neuroscience,
  • Psychology,
  • Medical / Nursing,
  • Neurology - General,
  • Clinical Psychology

  • The Physical Object
    FormatHardcover
    Number of Pages428
    ID Numbers
    Open LibraryOL8628174M
    ISBN 101860946186
    ISBN 109781860946189

      This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and. Animal models for neuropsychiatric disorders: prospects 1 for circuit intervention Tobias Kaiser, Yang Zhou 1and Guoping Feng,2 Monogenic animal models for psychiatric diseases have enabled researchers to dissect the relationship between certain candidate genes, neural circuit abnormalities, and behavioral phenotypes along development. Early.

      Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and next sections 5/5(1).   A centralized resource for assessing and identifying animal models for the study of human disease About the Author P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center.

    Animal models of neuropsychiatric disorders •Despite the challenges, significant progress has been made in the development and optimization of behavioral models for the majority of CNS disorders and these models have animal models for Alzheimer’s disease. Animal models of neuropsychiatric disorders are important to elucidate the pathophysiological mechanisms underlying these disorders as well as develop better treatment options. There has been tremendous progress made in the field of mouse genetics, and more recently in rats, to manipulate the genome in order to assess the impact of specific genetic manipulations on the animal.


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Animal Models of Neuropsychiatric Diseases by Michael Koch Download PDF EPUB FB2

Written by a team of experts, this book provides an up-to-date detailed overview of the current approaches to the design of viable animal models for eight prominent neuropsychiatric diseases.

The book is specifically written with the research-oriented reader in mind — both in academia and the pharmaceutical industry. Animal models of schizophrenia \/ Michael Koch.\/span>\"@ en\/a> ; \u00A0\u00A0\u00A0 schema:description\/a> \" Provides an up-to-date detailed overview of the current approaches to the design of animal models for eight prominent neuropsychiatric diseases.

Provides first-hand information on how to design viable animal models for Alzheimer\'s. Get this from a library. Animal models of neuropsychiatric diseases. [Michael Koch, Dr. nat.;] -- Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological psychiatry.

Written by a team of experts, this book provides an. "Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological psychiatry.

Written by a team of experts, this book provides an up-to-date detailed overview of the current approaches to the design of viable animal models for eight prominent neuropsychiatric diseases. The book is specifically written with the research.

Recommendations for describing animal models of neuropsychiatric disorders. State the goal. Is this a neurobiological tool or a disease model. 2Cited by: Disease models should be derived from plausible risk factors or causative agents of human disease or else exhibit a significant degree of neural or behavioral pathology that corresponds convincingly to human disease.

Animal models of neuropsychiatric disorders have been generated through diverse means, including selective breeding, genetic Cited by: Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders.

The text focuses on the rationale and theory of using animal behavior. to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general.

Journals & Books; Help; Neuroscience. Supports open access. 6 CiteScore. Impact Factor. Articles & Issues. About. Publish. Latest issue All issues. Search in this journal. Animal Models of Neuropsychiatric Disease. Edited by Joshua A. Gordon, Kafui Dzirasa. VolumePages (3 May ) Download full issue.

Previous vol/issue. Next. Willner P, Mitchell PJ, Koch M. Animal models of depression. In Animal Models of Neuropsychiatric Diseases.

In Animal Models of Neuropsychiatric Diseases. London: Imperial College Press. We survey the utility of animal models of mental illness, based on the identification of possible neurocognitive or neurobehavioral endophenotypes. Three broad clusters of neuropsychiatric disorder are discussed: impulsive-compulsive syndromes, comprising drug addiction, attention deficit/hyperactivity disorder, gambling, obsessive-compulsive disorder, and compulsive eating; disorders at the.

Models of Depression as a Response to Adversity. Acute stress models. Learned helplessness models. Forced swim test. Tail suspension test. Restraint stress.

Chronic stress models. Chronic severe stress. Chronic mild stress (CMS) Stress induction and mild stress maintenance. Withdrawal from chronic psychomotor stimulants (amphetamine and cocaine). Neuropsychiatric Disease Institutional Animal Care Veterinary Care Pain Test Sentient Animal These keywords were added by machine and not by the authors.

This process is experimental and the keywords may be updated as the learning algorithm improves. Timely introductory articles debate the alleged continuity of species of human and infrahuman behavior (Darwin), the utility of infrahuman animals in understanding human behavior and psychiatric disease, and the suitability of nonhuman models of complex neuropsychiatric dysfunctions involving language.

related phenotypes in animal models than disease-associated genetic variants of small effect (Box 2). The greater difficulty and controversy lie in diseases that currently lack such tools. Evaluating animal models of neuropsychiatric disorders By disease model, we refer to more than a useful tool for probing abnor - mal neurobiology and behavior.

Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric diseases of late life may contribute to behavioral changes commonly observed in the elderly population. Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences.

Offering easily searchable advantages and disadvantages for each animal model and organized by disease. Buy Modeling Neuropsychiatric Disorders in Laboratory Animals by Hoffman, Kurt Leroy (ISBN: ) from Amazon's Book Store.

Everyday low prices and free delivery on eligible orders. The final part of the book deals with OCD, epilepsy, and three cognition- and neuropsychiatric disorder-related reviews. A report by Hatalova et al. () uses an animal model of OCD based on sensitization by quinpirole, a D2-like receptor agonist, and suggests evidence for disrupted cognitive flexibility tested in spatial memory, cognitive.

Willner, P, Mitchell, PJ, D'Haenen, H & den Boer, JAAnimal models of depression: a diathesis/stress approach. in Biological Psychiatry. John Wiley & Sons, pp. Animal models serving in research may have an existing, inbred or induced disease or injury that is similar to a human condition.

These test conditions are often termed as animal models of use of animal models allows researchers to investigate disease states in ways which would be inaccessible in a human patient, performing procedures on the non-human animal that imply a level of.Parkinson's Disease Models - Taconic offers several Parkinson's models (sponsored by The Michael J fox Foundation) as well as a surgically induced model that can be used as tools to develop therapies against Parkinson's Disease.

Neuropsychiatric Disorder Models - Taconic offers three neuropsychiatric disorder animal models that develop distinct. Animal models have been used to address a variety of scientific questions, from basic science to the development and assessment of novel vaccines, or therapies.

The use of animals is not only based on the vast commonalities in the biology of most mammals, but also on the fact that human diseases often affect other animal species.